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If compulsive drug-seeking and drug-taking behavior are often not motivated by either the desire to obtain pleasure or by the desire to relieve withdrawal, then what motivates addictive behavior in these instances? Why do addicts compulsively seek drugs? We have attempted to address these questions by proposing the concept of “incentive-sensitization”.3,30 Tire basic thesis of the incentive-sensitization view of addiction can be summarized in four points.

This paper presents a biopsychological theory of drug addiction, the ‘Incentive-Sensitization Theory’. The theory addresses three fundamental questions. The first is: why do addicts crave drugs? That is, what is the psychological and neurobiological basis of drug craving? The second is: why does drug craving persist even after long periods of abstinence? The third is whether ‘wanting’ drugs (drug craving) is attributable to ‘liking’ drugs (to the subjective pleasurable effects of drugs)? The theory posits the following. (1) Addictive drugs share the ability to enhance mes~~tetencephalic dopamine neurotransmission.

One process, behavioral sensitization or reverse tolerance, may increase the chances of uncontrolled ethanol intake and is showing promise in helping to understand how other substances of abuse work. Research has demonstrated that with repeated administration of psychomotor stimulants, such as amphetamine or cocaine, both behavioral and neurochemical responses to a given dose of these drugs are progressively enhanced. This phenomenon contrasts to the well-known observation that repeated drug administration can lead to many diminished responses (i.e., tolerance).
Moreover, not only is deviance a continuum – from “high consensus” deviance  (rape, murder, robbery) to “low consensus” deviance (stealing a newspaper, smoking  marijuana, getting drunk at a party) – and not only does censure vary from one social  circle to another, but homosexuality itself is a continuum with respect to degrees of  deviance. In the past generation, the abbreviation LGBT (sometimes rendered LGBTQ)  has come into being; it gained acceptance so quickly that, in many circles, hardly  anyone has to explain what it means. It refers to the variant sexuality or homosexuality  cluster: Lesbian, Gay, Bisexual, Transsexual (plus “Queer,” though the “Q” sometimes  means “Questioning”).

The experience of the self as drunk

In this section we examine how Alison presents her engagement with alcohol as an experience of flux, oscillation and instability. We introduce the analysis with an extract which presents some of the main features of Alison’s engagement with alcohol. It also vividly illustrates how Alison turns to metaphors to describe her experience, a feature frequently repeated during the interview:

Some big wave, you know, you just get caught with it, that’s what it used to be like, this kind of like helpless feeling, just having to go and get drunk almost, you know, not even particularly wanting to, just feeling like there’s no other way when you are in that situation.